Thermostat temperature... 68 degrees vs 74?

I like the warmth. I keep my thermostat at 68 degrees when I'm home and sometimes I'm still a bit on the cold side. Am I going to see a big difference on my gas bill if I keep the thermostat at 74 vs keeping it at 68? I have a boiler (water/radiant heat) for the record. The way I'm thinking of this I shouldn't see a big difference. If the boiler is on long enough to raise the temperature only 1 or 2 degrees, I don't see how raising from 66 to 68 or 72 to 74 degrees would be much different. I know the temp outside will have a slight effect but I'm just curious if anyone can give me some info based on past experiences. Thanks!